Training & movement
BGive it a rest: a systematic review with Bayesian meta-analysis on the effect of inter-set rest interval duration on muscle hypertrophy
Singer A, Wolf M, Generoso L, Arias E, Delcastillo K, Echevarria E, Martinez A, Androulakis-Korakakis P, Refalo MC, Swinton PA, Schoenfeld BJ · 2024 · Frontiers in Sports and Active Living
REZA evidence rating B: Reasonable confidence
Methodology
Meta-analysis
Population
Studies with randomized design comparing different inter-set rest interval durations; trained and untrained adults
Intervention
Short (<60s) vs long (>60s) inter-set rest intervals during resistance training
Findings
A Bayesian meta-analysis found no clear evidence that rest-interval duration significantly affects muscle hypertrophy. Longer rest may be slightly favourable, but the effect is trivial to small — rest should be based on individual recovery rather than a strict protocol.
Outcome measures
Muscle hypertrophy (lean/muscle mass changes)
Limitations
Limited number of studies; heterogeneity in rest interval definitions; most studies short-term.
Original source
DOI: 10.3389/fspor.2024.1429789
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