Physical Activity, All-Cause and Cardiovascular Mortality, and Cardiovascular Disease: A Systematic Review and Meta-Analysis of Multiple Health Outcomes

Methodology

Evidence overview

Population

13 reviews (2 SRs, 7 meta-analyses, 4 pooled analyses); general population

Intervention

Different levels of physical activity

Findings

Higher physical activity is associated with a 30-40% reduction in all-cause mortality, a 30-40% reduction in cardiovascular mortality, and a 20-30% reduction in cardiovascular disease incidence, in a clear dose-response relationship. Both aerobic and resistance training contribute to mortality reduction.

Outcome measures

All-cause mortality, CVD mortality, CVD incidence

Limitations

Overview of reviews; observational data; varying PA definitions.

Original source

DOI: 10.1249/MSS.0000000000001939 · PMID: 31095084